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The lab of Professor James Lai in the UW Department of Bioengineering has an excellent opportunity for a full-time Research Scientist/Engineer 3.
To better improve future healthcare, the lab's research focuses on improving clinical assays required to detect biomarkers for the diagnosis, prognosis, and therapeutic management of human disease. This research will potentially improve the sensitivity and specificity of clinical assays, as well as their capability to detect multiple biomarkers, through the use of molecular reagents.
The individual in this position will be responsible for performing laboratory work and working with postdocs and graduate students to execute various projects, especially the development and testing of polymer reagents. The focus of this position is the sample preparation for enabling HIV assay. Specific duties include:
Synthesizing affinity reagents for recognizing HIV virions by conjugating antibodies to microbeads.
Designing and fabricating a simple filter device that can be used in conjunction with the affinity reagents for purifying virions from plasma.
Using simple chemistry, develop a process for allowing the downstream assay to utilize purified virions.
Validating the sample preparation approach using the HIV assay, RT-PCR.
Coordinating clinical samples for testing the viral load in plasma and PBMC at UW Clinical Retrovirus Laboratory.
Bachelor's degree in Bioengineering, Biology, Chemistry, Biochemistry, or related field.
Minimum of three years of professional research experience.
Demonstrated experience mentoring and training others.
Demonstrated experience performing RT-PCR.
Experience handling and testing clinical samples.
Strong organizational skills and attention to detail.
Experience writing for peer-reviewed journals and contributing text and figures to grant proposals.
Equivalent education and/or experience may substitute for minimum requirements.
Doctoral degree in Bioengineering, Biology, Chemistry, Biochemistry, or related field.
Demonstrated experience mentoring and training postdocs and students.
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